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Chronic Idiopathic Urticaria Angioedema
Chronic idiopathic urticaria angioedema is a type of angioedema that occurs in response to unknown causes and persists for more than six weeks. The swelling can be very annoying and may accompany itching and burning, as with other types of chronic urticaria. Many people face problems, as they are unable to open their eyes due to excessive swelling and others may feel difficulty in breathing if the airway is being blocked because of the swelling caused by chronic idiopathic urticaria angioedema.
Urticaria Angioedema
Urticaria angioedema, also known as Quincke's edema, is the rapid swelling of the subcutaneous tissue, mucosa, and submucosal tissues.
In extreme cases, it may also cause suffocation as the airway can be blocked due to immense swelling. Therefore, if it progresses rapidly, it should be treated as a medical emergency. If urticaria angioedema has occurred in response to an allergy, epinephrine can be extremely useful. However, if the patient has hereditary urticaria angioedema, treatment with epinephrine has not been very helpful.
Autoimmune Urticaria Angioedema
Urticaria angioedema has two major types: hereditary urticaria angioedema and autoimmune urticaria angioedema. The first is a hereditary disease whereas autoimmune urticaria angioedema is caused when certain parts of body fail to recognize its own constituent parts as self, which allows an immune response against its own cells and tissues. There is a certain type of cells called mast cells, which act as a defense system in humans. However, in certain circumstances, these cells become disturbed and release a fluid called histamine. This fluid can damage the surrounding membranes and cause itching and rashes. This process is called autoimmune, and when the result is urticaria, it is called autoimmune urticaria.
Autoimmune Chronic Urticaria Angioedema
Autoimmune urticaria angioedema, when persisting for more than 48 days continuously is a chronic condition called autoimmune chronic urticaria angioedema. The patient may suffer from burning and itchiness.
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